Courses with Walter Holbein

Regulatory and Clinical Manager
Nonin Medical, Inc.
Walter Holbein, Ph.D. is the Regulatory and Clinical Manager at Nonin Medical, Inc. He holds a PhD from University of Texas Health Science Center at San Antonio in Physiology. Dr. Holbein did his post-doctoral training at the Mayo Clinic in Human Integrative Physiology with Michael Joyner MD. During his training, Dr. Holbein led multifaceted in vivo and vitro studies that focused on the complex interactions between the medullary cardiovascular and respiratory networks during health and disease. Prior to accepting his position as Regulatory and Clinical Manager, Dr. Holbein led engineering teams to oversee advanced technology development projects for regional and pulse oximetry.
Measuring Cerebral Perfusion During CPR: Near Infrared Spectroscopy

Measuring Cerebral Perfusion During CPR: Near Infrared Spectroscopy

Cardiac arrest is a major health issue with poor survival outcomes. We have traditionally focused on resuscitating the heart (e.g. return of spontaneous circulation) but not the brain and approximately two-thirds of out-of-hospital cardiac arrest patients who survive to hospital admission die from brain injury. The brain is especially vulnerable to ischemia and brain injury is the final cause of death and disability for many cardiac arrest patients. There is currently no standard method to measure cerebral perfusion and oxygenation. Near-infrared spectroscopy (NIRS) is non-invasive and can measure cerebral oxygenation. This may allow focused resuscitation of the brain during CPR and help optimize cardiac arrest resuscitation to improve overall patient outcomes.


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